Santon did acknowledge that special attention will need to be paid to the former Magpies duo.
"West Ham will be a difficult game. They have some good players," he said. "They have Andy Carroll and Kevin Nolan, so we have to be careful.
"It is very important for us to win the game. We are only playing for a win.
"We have to stop them. We know they are coming here to score. However, we know we have a great defence here. We have a great team and we can stop them."