Sampdoria expect to lose Reto Ziegler at the end of the season.
The Swiss is off contract in June.
"He's a great guy and an excellent professional," Samp sporting director Doriano Tosi stated on Monday. "But he's asking for an important wage.
"The fear is that the player has already made up his mind and his departure is a real possibility.
"We've tried to reach a deal with him in these months, we spoke 20 days ago too, but it is clear that right now our priority is our League position.
"We have the hope that he could stay, but at the moment there is a significant chance that he won't."