Sampdoria patron Edoardo Garrone apologised to fans after their relegation.
The Blucerchiati's hopes of avoiding the drop evaporated after a 2-1 home defeat to Palermo, as Lecce won 2-0 at Bari.
"I never wanted to be here making this statement," said Garrone - the son of President Riccardo - in the Press room.
"It is such a sad moment and the fans do not deserve it. I am not here to comment on the game, as we must instead look at the overall - terrible - campaign.
"A series of errors were made and they have to be recognised. We take responsibility, but also reaffirm our commitment to Sampdoria, which remains unchanged.
"It is time to clean out the house and rebuild a team that can get back into Serie A as soon as possible.
"After so many years of great satisfaction at Sampdoria, this season ends with terrible disappointment."