The Portugal winger, whose 41 goals were a major factor in helping United retain their Premier League title, retained both the fans' and players' player of the year awards.
Ronaldo also won the goal of the season award for his free-kick at home to Portsmouth in January which swerved and dipped to leave goalkeeper David James flat-footed.
He said at the end of the season ceremony: "The fans have been fantastic for me, not just me but every player, singing all the time.
"This gives extra motivation to play better. The supporters help us all the time and I have to say thank you."
Ronaldo added: "I always try to help the team. If I score it's better for me, but I look all the time to play well for the team, to do something for the team. If the goals are coming, I feel very proud.
"I believe we are going to do everything to win that game (in Moscow)."
Sir Alex Ferguson said of his talisman: "When we saw Cristiano against us that night in Lisbon, there was no way we were going to leave that stadium without him, there's absolutely no doubt about that.
"Since he's come he has taken on the challenge of improving in every training session. He practices all the time and I think he is the best in the world now."