The Cottagers head to White Hart Lane on Sunday in search of a victory over their London rivals who Riise feels will be showing signs of fatigue after clashing with Inter Milan in the Europa League tonight.
"It's one of the toughest matches because of the way they play and they're in good shape but they have a heavy schedule right now as they're playing in the Europa League so hopefully they'll be a bit tired," he told the club's official website.
However, Riise remains wary of the star quality Spurs have amongst their ranks including two former Fulham players.
"They still have one of the best players in the league at the moment in Gareth Bale," he continued. "He can't stop scoring and he's a fantastic person as well. They've got Aaron Lennon on the other side too and good players all over the pitch.