The Hammers are seeking a new manager after dismissing Gianfranco Zola this morning.
The Mirror says co-owner David Sullivan is already considering potential candidates to replace Zola - including Mallorca coach Manzano.
Experienced Manzano, 54, has had a superb season in Spain guiding Mallorca to fifth in La Liga.
Manzano is respected on the continent after coaching Toledo, Valladolid, Racing Santander, Rayo Vallecano, Atletico Madrid and Malaga.
He was voted Spain's coach of the year in 2008 in his second spell with Mallorca.