The forward is under contract until 2015, but took to Twitter recently to claim "all the news about my renewal with Real Madrid are false".
Perez said: "Cristiano made these statements because there was some information in the media which did not match reality.
"Soon we will clarify this issue. I have no doubt that Cristiano is going to retire at Real Madrid. I am convinced that he will renew."
He added: "It (renewing with Ronaldo) is our most important activity, around whom we can build the Madrid of the future."