Real Madrid president Florentino Perez is ready to overhaul Zinedine Zidane's squad this summer - even if they win the Double.
Okdiario says Perez has plans to sell - or release - at least six first teamers at the end of this season.
Pepe will be allowed to leave as a free agent, with Inter Milan his destination.
Strikers Alvaro Morata and Mariano Diaz will be sold, while goalkeeper Keylor Navas will also move on.
A deal with Manchester United over James Rodriguez is now being finalised and Fabio Coentrao is in talks about a return to Portugal.