Real go into the game on the back of consecutive victories over Barcelona.
"If you can win in Barcelona you can win in Manchester. We have great respect for United but we aim to play our game; that way we can beat anybody," said Ozil.
The midfielder also spoke of his good relationship with Mourinho: "The coach trusts me and I owe my good performance to him. He supports me and he's one of the best coaches, if not the best coach in the world."