Pepe was dismissed for a lunge at Barca fullback Daniel Alves, who made the most of the challenge.
After victory over Sevilla, Pepe declared: "It's very easy to talk and say things. People misinterpret my aggression and tell lies. I did not touch Alves."
He added: "For the win tonight I returned to central defence, where I like to play. But I am happy to do whatever the coach tells me."