Real Madrid coach Zinedine Zidane denies Isco is isolated inside the locker room.
The midfielder is said to be ready to quit Real this summer after falling out with Zidane and senior teammates.
But after his strop against Espanyol, the coach insists: "I do not think it was anything abnormal.
"He was not happy that he was changed, but most players are like that. He has a great attitude, trains well and everyone in the club loves him.
"If a player is angry when he is substituted, that is normal."