Six players are understood to be in the sights of Mourinho after the shock setback.
"Some I know why they were tired because they played 90 minutes on Wednesday and worked a lot. Others, I do not know why they were tired, because on Wednesday they were on the bench or in the stands," said Mou.
Of those who played in Los Cármenes, there were three players who were in the stands for the Copa against Barcelona: Sergio Ramos, Angel Di Maria and Fabio Coentrao, all missing through suspension. On the bench were Gonzalo Higuain, Marcelo and Luka Modric, three of the players who had minutes in Granada.