Higuain could not prevent Argentina stumbling to a 1-0 defeat against Venezuela on Tuesday, but he was back to full steam against Betis.
He smiled afterwards: "We knew the game would be difficult. Betis had won many matches, but we proved to be in top form despite the league break.
"I'm very happy. I hadn't played in one week, but I feel just like I did before then. The coach will decide if I must be a starter or not. I just play, which is what I must do.
"These hat-tricks are good memories to cherish after retirement. It will also be nice to remember this because it will recall the injury I suffered beforehand and how rough it was on me. I feel better each time. I'm grateful to my teammates an the club because they always supported me during the time I was injured."