Valladolid have improved immensely since former Spain coach Javier Clemente took over recently, winning three and drawing three of seven matches, and they, like Malaga, are in the thick of the relegation battle so are in also need of the points.
Defender Sergio Ramos said: "We can only think about continuing to fight. The first thing to think about is picking up the three points against Malaga, an encounter you can't take as won because they're a team that are fighting for a lot.
"Then we have hope that Valladolid can cause a surprise as they are also playing to avoid relegation at the Nou Camp.
"We want to get to 98 points, and if Barca are proclaimed champions with 99 then we need to congratulate them. Both teams have had a great season. We both deserve to win the league but there is only one trophy."