United go to Villa Park after back-to-back Premier League defeats.
"I think this is a very big game for us now," Rafael told manutd.com. "We need to get back to winning ways in the Premier League as well and show the same form we have had in the Champions League. We need to do the same in the league.
"It's true [Villa Park is one of our favourite venues]. I remember it was a very good game last year when Chicharito claimed three goals (one went down as a Ron Vlaar own goal) as we came back from 2-0 down. I hope we can get another win there."