Hughes was City boss for 18 months before the club's Arab owners callously replaced him with Roberto Mancini in December 2009.
Sparky said: "It would be just fantastic to go there and get something. They are going for the title and we're trying to stay in the league.
"When I took over at QPR, I looked at the fixtures and that one lurked ominously in the distant future.
"It does feel a little bit fated for them and for us."