QPR's defeat was Hughes' heaviest as a manager and he accused this side of being "naive" after falling 4-0 behind inside 25 minutes.
"Given the week that Chelsea have had - the whole club's on a high - we had to come and set our stall out and make sure that we were difficult to beat," he said. "What was it, 30, 40 seconds we're behind in the game?
"At that point, the feeling is that it's possibly going to be a difficult day.
"The fact that we kept going, we deserve a bit of credit. But, at times, we were a little bit naive.
"Possibly you have to take your medicine and understand that it's not going to be your day."
Hughes refused to use the handshake saga as an excuse for defeat that saw Rangers' goal difference take a battering in their bid to stay out of the drop zone.
"Hopefully, a number of results will go for us and maybe the damage isn't critical in terms of goal difference," he said, looking ahead to next Sunday's home clash with Stoke.
"We've got a huge game next week, which we need to get maximum points out of and we've got to be more accomplished than we were today at Man City in the last game."