Redknapp is concerned about the possible damage to the 33-year-old centre-half's ankle ligaments after England came unstuck on the artificial pitch in Moscow.
"He came back aching from head to foot, and I am wondering how much it has done to his Achilles tendons - which have always given him problems," Redknapp said.
Portsmouth masseur Chris Neville, also part of England's medical team, has been able to update Redknapp on Campbell's condition.
The Pompey boss added: "Sol and I have spoken to Chris - and all we can do with him is massage him over the next few days, then let him out for a little jog, a little loosener and see if we can wheel him out on Saturday.
"But Sol is our captain, our leader - and as bad as I feel about England's defeat, my first thought was about him and how playing three matches in such a short time will affect him.
"I was delighted to see him back in the England team against Estonia last Saturday - because he has done really well - but I've got to admit I was selfish in hoping that it would be John Terry playing on Wednesday night instead."