The Japan defender is yet to see action in the Premier League this season.
Pochettino said: "We have four centre-halves, we have four defenders, it is also clear that Maya was the last one that arrived during the pre-season.
"He had a really tough pre-season, especially at the beginning. Nonetheless, there is four central defenders and only two can play so I have to make those decisions.
"At the moment, (Dejan) Lovren and (Jose) Fonte are playing, so that's basically it. It doesn't have to be that there is a problem with Maya, there is no problem with Maya Yoshida."
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