Southampton boss Mauricio Pochettino is convinced they can shock Manchester United.
United suffered a surprise defeat at home to West Brom, and Pochettino believes his side can claim another big scalp after beating Liverpool at Anfield.
He said: "It is one thing to be confident and another to be complacent.
"We're going to have to work hard to win or get anything out of the game.
"It is clear we have won three out of three and teams are respecting us.
"We need to have a lot more energy and intensity. We have the mental capacity to win this game.
"It is a good pressure to be vying at the top of the table, and it is good that we have gained respect but we can't be complacent and let this go to our heads."
