But former France star Pires, 36, said: "The injuries always seem to have damaged Arsenal in the last few seasons and now again this is the difficult time between November and December.
"Teams that suffer a lot of problems during these months often miss out on winning the league. You play a lot of games, it's difficult and it tests the squad.
"Arshavin is playing so well and the speed of Walcott can damage and hurt a lot of opponents.
"Arsene Wenger always has a strategy and ideas to overcome problems in the squad and missing players.
"Now Arsenal are missing some big players but I believe the club can still have a good season even though they will be without some attacking players."