Uncapped winger Callum McManaman was the stand-out inclusion in Stuart Pearce‚Äôs squad for Israel when it was announced on Tuesday.
But the 22-year-old damaged ankle ligaments that evening in Wigan‚Äôs 4-1 defeat at Arsenal and faces three months on the sidelines.
Pearce has turned to Aston Villa forward Delfouneso, who was part of the Euro 2011 Under-21 squad in Denmark.
‚ÄúNathan was very unfortunate not to make the squad in the first place,‚ÄĚ said Pearce.
‚ÄúHe has contributed a great deal to the Under-21s in qualification and was unlucky that Callum McManaman‚Äôs form was such that he had forced his way into the reckoning late on.‚ÄĚ