Ahead of today's game, Guidolin remarked: "For three years Inter have dominated the sport in Italy, but this season of what I have seen so far they are more unpredictable and better at passing the ball around.
"If we don't put the pressure on them all over the pitch, we risk conceding a goal with their seven or eight quick passes."
Zlatan Ibrahimovic may have left, but Guidolin appreciates the talent that has come in to replace him.
"Having said that, if we play to our strengths with determination, concentration and commitment, we can cause an upset. We have to try."