Palermo chief Walter Sabatini admits Simon Kjaer's future is likely to be in England.
"If Milan cannot keep Kaka, and Inter cannot hang on to [Zlatan] Ibrahimovic, then how can Palermo keep their best players? It would not be a redimension," Sabatini told Corriere Dello Sport.
"Where will they [Kjaer and Edinson Cavani] go? I say the Premier League."
Uruguay striker Cavani has been linked with West Ham United.