Crystal Palace skipper Mile Jedinak is carrying a knee injury.
The Australia captain has returned to England after leading his country to victory in the Asian Cup.
Ledley said: "I think Saturday will be a little bit too early for him, he's come back, his knee is swollen and he's had it drained.
"He's been a big miss since he's been away. We have done brilliant without him but he's been a big miss and he's a big skipper around the place."
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