O'Neill confirms likely Sunderland debut for Kyrgiakos
Kyrgiakos, 32, has not had a look-in since joining the Black Cats on loan from Wolfsburg in January.
But he is set for a call-up with boss O'Neill keen to rest players ahead of next week's FA Cup quarter-final replay at home to Everton.
O'Neill said: "He's not moaned at all at not having played and has been with us all the way.
"This match will be his kind of battle and it's a real possibility he plays."