The Reds, without star striker Jermain Defoe and skipper Steven Caldwell, managed to get the better of the Crew were the only team to have a 100% winning record prior to the weekend's round of matches.
Also missing were the likes of Jonathan Osorio and Doneil Henry which gave further credence to the victory which was warmly welcomed by the boss of the Canadian outfit following goals from Michael Bradley and substitute Issey Nakajima-Farran.
"It was a very professional and hardened performance," Nelsen told reporters via conference call after the game.
"It's very hard to win away in this league and to be able to take two road wins in these four games is very pleasing. To perform like this away from home gives us a lot of confidence."
The former New Zealand skipper added: "I thought we were magnificent today.
"It's very hard to single one individual out because I thought everybody was just brilliant.
"Nick Hagglund and Bradley Orr at the back looked like they'd been playing together for a long time together and Jackson (Goncalves) had one of the best games I've seen him play on both sides of the ball.
"To have nine points out of four [games], I'm obviously extremely happy with that. Once we get playing together and get our combinations together we'll be a different animal."
For breaking stories and all the great banter like us on Facebook: facebook.com/tribalfootball