The England Under-19 international will make his first start after signing on a season-long loan from Tottenham.
Kane, 19, said: "It's a great opportunity for me and the reason I came here.
"I need to impress the manager so that I get a chance to play in the Premier League and this game will be good experience for me."
Boss Chris Hughton said : "Harry's bubbling with enthusiasm and he just wants to play games and score goals.
"He's had a good upbringing and he's a natural finisher. I think he's very fortunate because he looks to have a great future in football."