The Canaries posted a shock 1-0 win over United at Carrow Road in November, which Holt would love to repeat.
He said : "Strangely enough, I've never played at Old Trafford before because I missed the game there last season.
"I love playing at the big grounds, against the big teams, so I'm really looking forward to it.
"This is the only big ground in the country where I've never played, so I feel I have a point to prove.
"I'd love to think we could double them and you always raise your game against Manchester United."