Newcastle United boss Sam Allardyce admits they must manage their injury list better.
Michael Owen joined Claudio Cacapa, Joey Barton, Shola Ameobi, Celestine Babayaro, Stephen Carr, Damien Duff and Peter Ramage on the sidelines on Saturday.
"We've got to make sure we manage them (injuries) better," Allardyce told The Journal. "Previous managers have had similar problems and that's when results start to suffer. The object is to get them fit and keep them fit longer. At the moment that's not happening and that was a big factor in Saturday's result.
"We were short on experience of playing with each other. We got caught out, certainly defensively, by the amount of changes and the number of players who had not got that much Premiership experience. I thought it wouldn't be like that until we gave away that second, stupid goal. It gave Manchester City more of the upper hand than they'd had in any other part of the game. They could play on the break because they'd got back from 1-0 down. We had to over-commit so they could exploit more space.
"We've changed all aspects of how the players train but (the injury situation) can't really be changed in the space of a few months, it goes into years.
"If they're not quite as conditioned as they should be in the first place they need to catch up and sometimes because games are coming up you have to sacrifice that to get them ready. It's a long process but we'll continue that.
"It's been a problem but only because we're only just staring what we want to carry on and on and on over the next few years.
"It was a problem at Bolton when I first started but we developed the best injury record in the league. That's crucial to any manager or any club."