New York Red Bulls midfielder Teemu Tainio could be missing for six weeks with a knee injury.
Defender centerback Wilman Conde will sit out the Columbus Crew game with a groin injury.
"Teemu has a ligament. Unfortunately I would guess four-to-six weeks,'' head coach Hans Backe told the New York Post. "(Conde), it's a little bit strange with his groin. His ankle is ok, but he can't really hit the ball. Normally, he should be in for next weekend.''