Muamba missed a sitter in the defeat to Manchester United but Nolan is confident this won't affect his game.
"Fabrice worked hard in the game, he was fantastic," Nolan told The Bolton News.
"He will have expected to score that one, but he has just got to keep his head up because those goals will come.
"He's a strong character and a very bright lad. He doesn't need anyone to tell him to keep his head up, but if he does, I'm there.
"At some point this season he'll score a goal out of nothing which will get us points, so it evens itself out in the end," he said.
"He is a top player and he will get more chances. We all miss them, even the best players in the world do. He's got to put it to the back of his mind, then take the next one and celebrate."