Rooney was heavily involved in the 5-0 rout.
"Leverkusen are doing so well in the Bundesliga at the moment, second only to Bayern Munich, so that puts our result and performance into perspective," explained the boss. "It was an all-round great performance, coming away from home and scoring five goals somewhere that's renowned as being a difficult place to come.
"The link-up play was super tonight, I think Wayne Rooney got four assists. It's a long season and we're going to have to have different combinations for different games but, tonight, Wayne and Shinji Kagawa were very good.
"Sometimes Wayne might need to play up front and Shinji will play behind. We have to make sure we have alternatives if Wayne or Robin [van Persie] are injured. Shinji was excellent tonight but he's also good on the left.
"The goals will get the headlines but we defended well. It was an important game because we had to win to stay top of the group and we've now qualified.
"I've been hoping to get this type of performance more often, I've not had it as often as I would have liked. I think there have been signs that we were getting better but, at the same time, we have been a little wasteful on occasions. However, there have been games where we've looked like getting goals and thankfully we managed to do so tonight.
"I'd have to say it's the best [display] so far [in my time at United] because of the goals and we've not done it in a game of this magnitude. But I want us to do it regularly.
"I hope I can continue the standards set before I came here and that's what I plan to do. The team's performance tonight showed that. It's what's expected here, doing well in the league and cups and I'll try to keep that going."
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