Mourinho dismissed the claims of Benitez that fixture schedules and the intimidation of referees were key reasons for Manchester United's dominance.
"There is no bias," said Mourinho. "Chelsea were champions because we were the best team and Manchester United are champions because they are the best team. If Liverpool want to win, they have to be better.
"The best team wins."
"We do not rest players as we have to win the title. The big clubs are the ones fighting for the title and the Champions League at the same time.
"Before we played Liverpool in the Champions League semi-final in 2007, Liverpool rested ten players against Fulham. Liverpool lost and that result helped Fulham against another club in the fight against relegation.
"We're playing to win the title, so there's no rotation."