Mourinho responded after his side won away to Everton on Monday.
"All that Scholes does is criticise, not commentate and they are two different things," said Mourinho.
"I prefer to think of him as a fantastic footballer than as a commentator.
"If some day he becomes a manager I hope that he has 25% of the success that I have had. 25% of the 25 trophies are six, if he did that then it would be great."
Also defending Paul Pogba he added: "It is not Paul's (Pogba) fault that he earns more money than Scholes. That is football today."