Mourinho admitted that this season "could have been better", with the capital club on the verge of relinquishing the title to arch rivals Barcelona.
"We want to finish second," he said. "Second is not enough but it's the only target we can have. We still need some points and we have to try and win the match to finish second as soon as we can.
"On the other side we have a very good team that is coming to create us problems, like they always do. They are a good defensive team that play well on the counter-attack. If you do not play them seriously or in the best possible way, it's possible to lose."