The Argentine is hoping the Nerazzurri will end the group stages at the top of the table and book their place in the next round.
"We come here to Spain following a good run," said Milito.
"We are hoping to win this and qualify for the next stage. Our victory over Dynamo Kiev gave us confidence and spirit to approach this match.
"If we will beat Barca it will be a further boost to our morale."