Barca are battling with Villarreal for second-place and automatic Champions League qualification and after their 6-0 victory over Valencia, Messi said: "We must go there to do our best.
"It'll be difficult to catch Villarreal, but I hope things work out for us."
On the boos of the Nou Camp crowd, Messi added: "We knew they would be upset. They have their reasons."