"After three years in Ukraine and last season at Zaragoza, Lazio is a great opportunity for me," Matuzalem said at his unveiling.
"I'm happy to wear the shirt of such a prestigious club. My first day of training was great.
"I am only here for a year on loan, but I will do all I can to stay here longer.
"I want to recover the joy of playing football again after a difficult year when I suffered with a knee injury. I want to get back to the top of my game.
"At Lazio we are hoping to win all games. The aim is to finish high up in the table and I want to win back my place in the national side."