The Italian is adamant that he has superior players in his squad and says they play a better football than the Reds from across town.
Boss Mancini said: "Things aren't going well but I know we will still have a great year.
"United have more experience but we have a much better team and play much better football.
"Six points is not a big difference with 24 games still to play. We need to try to win five or six games in a row to try and reduce the gap. Even though we lost on Sunday, we showed that we are a really strong team and can win the title again.
"We were unlucky. We dominated long spells of that game - and did not deserve to lose.
"The Premier League is the best campaign in the world at the moment and as we know from winning last year, you can lose a game in the last second."