Giggs fears City's lack of European action will help their title bid.
The Welshman said: "At the turn of the year you start looking at who is around you, what teams are playing who - where you expect to get points, where it will be tough.
"We are still in the Champions League, City aren't, Chelsea are in the Europa League. City will have the week to prepare whereas we might have tough European games.
"We're used to playing Wednesday-Saturday. It all depends on when the games are, who we've got.
"If it's Wednesday then 12.45 in the Premier League on the Saturday, it can be tough.
"It's just up to us to make sure we don't drop points around that time."