Although admitting Neville's nerves will probably be jangling ahead of his final appearance, Giggs believes it will be a fitting occasion against the Serie A giants.
"Gary deserves a full house," Giggs told manutd.com. "The service he's given, the person he is, he's dedicated most of his life to Manchester United.
"He's grown up watching them as a fan, he's been here since 11 or 12 and to go on and be the best right-back in his era by a long way is tremendous testimony and hopefully the fans will honour that.
"I can speak from experience of my testimonial that you're nervous, but, at the end of it, it's great to share with the fans and celebrate a great career. It'll be a good night for him because it'll be the last time he's playing at Old Trafford. He's been a great friend and team-mate for me, and a credit to himself and his family."