Berbatov spent four seasons at Old Trafford before leaving last August for Craven Cottage, where he's dazzled supporters with his sublime skill and, so far, seven goals.
"It will be good to see Berba," Giggs told MUTV after the Reds' 1-0 win against West Ham on Wednesday night.
"He gave United great service and he was such a talent. We'll have to keep an eye on him. It will be nice to see him again and I'm sure the crowd will give him a good reception."