Although a minor knee injury threatens Rooney's presence in the friendly against Egypt on Wednesday, he will be a key part of Fabio Capello's plans for South Africa this summer.
And Neville feels that could provide the crowning glory to an extraordinary career that has seen Rooney move on to a different level this season, when he has scored 28 goals, the last five of which have been headers.
"Wayne is a great player to play with and is one of the brilliant Manchester United players have had," said Neville.
"He has been brilliant for England too. The only thing he has to do for England now is go and win something. That is what England players have been striving to do for the past 40 years.
"That would really crown it off for him."