Neville says Wenger is out of order for criticising Wolves boss Mick McCarthy for fielding a weakened team at Old Trafford last week.
He told the Daily Express: "It's the prerogative of a manager. Mick McCarthy has the whole season to think about. It's wrong for people with big squads like Arsene Wenger to criticise Wolves when they have a different agenda.
"Wenger doesn't know what is going on at Wolves, neither do we, and Wolves should be able to prioritise what game to play each player in. Clubs have squads so they can rotate players. It's not for anyone to criticise - Wolves can decide what they want to do. They can go and play their youth team next week if they want; it's entirely up to them."