Gazzetta dello Sport says Juve are planning a big summer market campaign and are willing to sacrifice Marchisio to boost their spending power.
Marchisio is the player Juve coach Antonio Conte is willing to sell after insisting last week that midfield partner Arturo Vidal was not for sale.
The Italy international has been a long-time favourite of Manchester United boss Sir Alex Ferguson and Real Madrid president Florentino Perez. Manchester City, PSG and Bayern Munich are also sure to make their interest known if Marchisio is indeed put up for sale.
Ferguson first made enquiries after Marchisio when he was first breaking into Juve's first team and has remained a big fan. With Paul Scholes expected to retire at the end of this season, Marchisio appears the ideal successor for the United legend.
Juve hope to see offers of €30 million for the goalscoring midfielder.
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