Kagawa, like all Sir Alex Ferguson's men, is keen to be involved.
"I'm looking forward to it," he told United Review. "If I'm picked I'll do my best to help the team reach the next stage of the competition."
By his own admission, though, the Japanese midfielder lacks Champions League experience. Indeed, he's never played in the competition's knockout stages, having finished bottom of Group F with Borussia Dortmund in 2011/12.
"I played in the Champions League with Borussia Dortmund last season but unfortunately we couldn't perform to our potential," Kagawa said.
"We were too young, we didn't have enough experience and got knocked out in the group stage. However, United has a great history and we finished top of our group this season.