On a positive note for United fans, Luke Shaw is set to feature in the encounter at Old Trafford.
"We have problems, we have injuries," Jose said. "Matic is injured and when I say he is injured, he is injured.
"I am not going to make him play so Matic is out. A couple of others guys are playing every match and they also need a rest.
"More importantly, the other guys deserve an opportunity to play."
Asked if Luke Shaw might feature, the Red Devils manager said: "He's working to have an opportunity and sooner or later, the opportunity will arrive. Because he deserves that opportunity.
"Selected for tomorrow, yes, for sure. To start or to be on the bench, I cannot answer."