The News of the World says United are set to plunder the Americas again by offering Â£5million for Estudiantes forward Boselli.
Earlier this month, the Red Devils signed Mexican striker Javier Hernandez from Chivas de Guadalajara.
United's over-reliance on Wayne Rooney has encouraged an emphasis on recruiting firepower for next season.
Argentina international Boselli is in cracking form for high-fliers Estudiantes this season and has a strike rate of three goals every four games.
He has been earmarked by other Premier League clubs for his pace and uncanny eye for goal and has former United midfielder Juan Sebastian Veron in his current side to advise him about life in England.