Pogba scored in the 4-1 rout.
Neville said on Sky Sports: "I thought it was his best performance and I think that when you sign someone for that level of money, they have to influence the game. I thought today, first half, he was the best player on the pitch."
He added: "I think in the first half he seemed even a little bit more determined. It seemed to me like Jose Mourinho had said to him during the week you have to sprint back when you lose the ball."